Impact of Latanoprost Antiglaucoma Eyedrops and Their Excipients on Toxicity and Healing Characteristics in the Ex Vivo Eye Irritation Test System

Abstract Introduction Corneal epithelial toxicity and delayed healing process have already been attributed to preservatives or some excipients.We study the effects of galenic components in antiglaucoma drugs such as benzalkonium chloride (BAC) or surfactants like macrogolglycerol hydroxystearate 40 (MGHS 40) on corneal toxicity in an ex vivo system

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Duplication and diversification of the LEAFY HULL STERILE1 and Oryza sativa MADS5 SEPALLATA lineages in graminoid Poales

Abstract Background Gene duplication and the subsequent divergence in function of the resulting paralogs via subfunctionalization and/or neofunctionalization is hypothesized to have played a major role in the evolution of plant form.The LEAFY HULL STERILE1 (LHS1) SEPALLATA (SEP) genes have been linked with the origin and diversification of the gras

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Double orifice mitral valve: A case report

Introduction.Double orifice mitrol valve (DOMV) is a very rare congenital heart defect.Case report.We reported 20-year-old male referred to our center due to evaluation of his cardiologic status.He was operated on shortly after birth for a tracheoesophageal fistula.Accidentally, echocardiography examination at the age of ador 3d allure massage chai

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